Welcome to the forum
Your save (a manual save would have been better) works fine for me without causing a crash.
Which hardware do you use (CPU, GPU, Ram)?
- did you try to reduce the graphic details?
- is ENBoost enabled (default setting)? Try both settings.
- the same with OSAllocators und Onetweak (on/off)
- make sure that CPU and RAM usage in the “optimisations” tab are on max
- don't use ALT+TAB during loading screens, to click on a different display. It might take a long time for the game to load, even when it seems like it might already have crashed (mouse cursor becoming a circle or might be missing entirely).
- try restarting Steam and/or your PC.
One more hint: your Fast Travel Mod can cause serious problems in some quest lines when used at the wrong time (but is not the cause of a crash).