Question about plugin mechanics

[FreezeProblem]

So I want to make mod for morrowind which will make all present enemies more acurrate and this mod must be compatible with morrowind overhaul (http://morrowindoverhaul.net/forum/inde ... ,12.0.html). Overhaul includes plugin which adds new meshes for creatures, so it chandes creatures.
If I want to make creatures more lethal can I save their stats in another plugin or the only way is editing that which included? Is plugin load order matters?

Also is it matters what to load in TES3CS before to edit npcs and saving plugin(I mean load master files only)? I do not know if other plugins changes dialogues or something, is it possible to increase npcs compat stats and not break anything?

Can one npc be affected by 2 plugins at time?