I'm level 14 or so now. Mostly Vandal (2 handed), heavy armor with 1 memory or so on Keeper, 4 or so memories on each of Elementarist and Sinistrope. Female not-Redguard (forgot already... half-Quagarrian? Something like that) if it makes a difference.. using a Rune greatsword at the moment.
My 2 handed skill is not over 30, probably 25 or 27 or something. Still not sure of how I'll make money... I've put some in the bank. Maybe I'll try stealing stuff and selling it to the fence in the Undercity. Or find that guy with the 10k bounty.
Playing in Adept difficulty. Pretty modest computer, Radeon HD 4850 512mb, some AMD processor, 8 gigs of ram.. get around 20fps.
It's pretty hard but it's doable. Not too much of a challenge to the point that it's impossible, I do get killed from time to time. The only part that was ridiculously hard so far was that giant spider in a cabin in that mission of the island to the southeast of Enderal, someone's son. Freaking thing killed me in 2 hits, I had to come into the cabin, swing an axe at it once, leave, wait for the battle music and sneak eye to go away, eat food ,wait to get healed, rinse and repeat.
There were some skeletons that kept killing me too. And the not-Draugr are pretty OP, so for now I just avoid them or try to use tactics of running away to try to separate them and take them 1 by 1 or the rather ridiculous getting in a position that they run against an obstacle, not moving while I'm on a rock filling them with dozens of arrows. I just recently learned to do the block+LMB to cancel an enemies' power attack.. sometimes I also run backwards while spewing fire or throwing fireballs or lightning.
I have to keep eating food. Healing spells are useless, I use potions when I'm getting killed but try to avoid it. From Skyrim I am mostly used to sneaking and using a bow and then charging once I'm discovered...